Nitric Oxide and Peroxynitrite: Effects on Cardiovascular Function

Summary Cardiovascular diseases represent a major cuase of death in the western world. Both nitric oxide and peroxynitrite have been implicated in different cardiovascular processes. Nitric oxide is an endogenous vasodilator and mediator of several important physiological processes and it is involved in a number of protective mechanisms in cells. However, overproduction of nitric oxide can occur a…