Transforming growth factor-beta receptor type I gene is freq…
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- PMID https://pubmed.ncbi.nlm.nih.gov/11406536
- OpenAlex ID W2170550480
- Type Article
- Language EN
- Published 15 Jun 2001
- Volume 61 (12)
- Pages 4679–82
- Source PubMed
- Publisher National Institutes of Health
- FWCI 2.66
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 01 Oct 2026
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Transforming growth factor-beta receptor type I gene is frequently mutated in ovarian carcinomas.
Article 2001 EN
Ovarian carcinomas (OCs), particularly recurrent OCs, are frequently resistant to transforming growth factor (TGF)-beta-mediated growth inhibition. Mutations in the TGF-beta receptor type II (TbetaR-II) gene are only evident in a minority of OCs, suggesting that other alterations of the TGF-beta signaling pathway may be involved in OC. Using PCR, cold single-strand conformation polymorphism, and D…
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1 SDGsAuthors & Affiliations
8 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Taiping Chen | Wood Hudson Cancer Research La… (US) | |
| 2 | J Triplett | — | — |
| 3 | Ben Dehner | — | — |
| 4 | Bernadette M. Hurst | — | — |
| 5 | Bruce M. Colligan | — | — |
| 6 | Jackson O. Pemberton | — | — |
| 7 | Jeremy Richard Graff | — | — |
| 8 | Julia H. Carter | — |
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