Pulse methotrexate versus pulse actinomycin D in the treatme…

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Pulse methotrexate versus pulse actinomycin D in the treatment of low‐risk gestational trophoblastic neoplasia

Article 2008 EN

OBJECTIVE: To compare the efficacy of methotrexate and actinomycin D as single agents in first-line chemotherapy for women with low-risk gestational trophoblastic neoplasia (LR-GTN). METHODS: A total of 131 women with LR-GTN were randomized to receive a weekly pulsed dose of 30 mg/m(2) of methotrexate intramuscularly (n=81) or a pulsed intravenous bolus of 1.25 mg/m(2) of actinomycin D every 2 wee…

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6 authors
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1 Fariba Yarandi Corresponding University of Tehran (IR) Tehran University of Medical S… (IR)
2 Zahra Eftekhar University of Tehran (IR)
3 Hadi Shojaei University of Tehran (IR) —
4 Soheyla Kanani University of Tehran (IR) —
5 Ali Sharifi University of Tehran (IR)
6 Parviz Hanjani Abington Memorial Hospital (US) —

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