Tumor-Promoting Phorbol Esters Affect Production of Prolacti…
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- DOI 10.1210/endo-108-4-1164
- PMID https://pubmed.ncbi.nlm.nih.gov/7472264
- OpenAlex ID W2137099733
- Type Article
- Language EN
- Published 01 Apr 1981
- Volume 108 (4)
- Pages 1164–1170
- Source Endocrinology
- Publisher Oxford University Press
- FWCI 7.21
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 12 Oct 2026
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Tumor-Promoting Phorbol Esters Affect Production of Prolactin and Growth Hormone by Rat Pituitary Cells*
Article 1981 EN
GH4C1 cells are strain of rat pituitary cells which synthesize and secrete both PRL and GH. Phorbol esters, which are potent tumor promoters in mouse skin and have diverse actions in a variety of cell and tissue systems, were found to alter hormone production by GH4C1 cells. 12-O-Tetradecanoylphorbol-13-acetate (TPA), the most potent phorbol ester, stimulated both PRL synthesis and release. The sy…
96
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34
References
2
Authors
7.21
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
2 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Rosemarie Osborne | Harvard University (US) | |
| 2 | Armen H. Tashjian | Harvard University (US) | — |
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