Long-Term Effect of Estrogen and Progesterone on Mammary Gla…

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Long-Term Effect of Estrogen and Progesterone on Mammary Gland Growth in 3-Methylcholanthrene Treated and Non-treated Ovariectomized Rats.

Article 1961 EN

Administration of 1 μg estradiol benzoate plus 3 mg progesterone into ovariectomized rats for 20 days produced mammary gland DNA levels comparable to those observed in rats on 19th day of pregnancy, while continued injection for periods of 30, 40 and 50 days did not significantly increase observed growth. However, no involutionary changes were noted with long-term injection, indicating a maintaine…

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1 H. C. Damm University of Missouri (US) —
2 Charles W. Turner University of Missouri (US)

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