Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Sy…
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- DOI 10.2337/db13-0880
- PMID https://pubmed.ncbi.nlm.nih.gov/23990365
- OpenAlex ID W2128797808
- Type Article
- Language EN
- Published 30 Aug 2013
- Volume 62 (12)
- Pages 4070–4082
- Source Diabetes
- Publisher American Diabetes Association
- FWCI 5.42
- Countries 3
- Institutions 6
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Glucose-6-Phosphate–Mediated Activation of Liver Glycogen Synthase Plays a Key Role in Hepatic Glycogen Synthesis
Article 2013 EN Hybrid
The liver responds to an increase in blood glucose levels in the postprandial state by uptake of glucose and conversion to glycogen. Liver glycogen synthase (GYS2), a key enzyme in glycogen synthesis, is controlled by a complex interplay between the allosteric activator glucose-6-phosphate (G6P) and reversible phosphorylation through glycogen synthase kinase-3 and the glycogen-associated form of p…
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15 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Alexander von Wilamowitz-Moellendorff | University of Dundee (GB) MRC Protein Phosphorylation an… (GB) | |
| 2 | Roger W. Hunter | University of Dundee (GB) MRC Protein Phosphorylation an… (GB) | |
| 3 | Mar Garcı́a-Rocha | Centro de Investigación Bioméd… (ES) Institute for Research in Biom… (ES) +1 | |
| 4 | Li Kang | Vanderbilt University (US) | |
| 5 | Iliana López‐Soldado | Centro de Investigación Bioméd… (ES) Institute for Research in Biom… (ES) +1 | |
| 6 | Louise Lantier | Vanderbilt University (US) | |
| 7 | Kashyap Amratlal Patel | University of Dundee (GB) MRC Protein Phosphorylation an… (GB) | |
| 8 | Mark W. Peggie | University of Dundee (GB) MRC Protein Phosphorylation an… (GB) | |
| 9 | Carlos Martínez-Pons | Centro de Investigación Bioméd… (ES) Institute for Research in Biom… (ES) +1 | — |
| 10 | Martin Voß | University of Dundee (GB) MRC Protein Phosphorylation an… (GB) | |
| 11 | Joaquim Calbó | Centro de Investigación Bioméd… (ES) Institute for Research in Biom… (ES) +1 | — |
| 12 | Patricia T.W. Cohen | University of Dundee (GB) MRC Protein Phosphorylation an… (GB) | — |
| 13 | David H. Wasserman | Vanderbilt University (US) | |
| 14 | Joan Josep Guinovart | Centro de Investigación Bioméd… (ES) Institute for Research in Biom… (ES) +1 | |
| 15 | Kei Sakamoto Corresponding | University of Dundee (GB) MRC Protein Phosphorylation an… (GB) |
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