The Sequence of the Human Genome

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2001
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  • DOI 10.1126/science.1058040
  • PMID https://pubmed.ncbi.nlm.nih.gov/11181995
  • OpenAlex ID W2127230663
  • Type Article
  • Language EN
  • Published 16 Feb 2001
  • Volume 291 (5507)
  • Pages 1304–1351
  • Source Science
  • Publisher American Association for the Advanc…
  • FWCI 406.58
  • Countries 3
  • Institutions 12
  • Added 10 Oct 2025
  • Updated 25 Oct 2026
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The Sequence of the Human Genome

Article 2001 EN

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was generated over 9 months from 27,271,853 high-quality sequence reads (5.11-fold coverage of the genome) from both ends of plasmid clones made from the DNA of five individuals. Two assembly strategies-a whole…

13.9K

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189

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273

Authors

406.58

FWCI

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273 authors
#AuthorInstitutionsORCID
1 J. Craig Venter Corresponding —
2 Mark D. Adams —
3 Eugene Wimberly Myers —
4 Peter W. Li — —
5 Richard Mural — —
6 Granger G. Sutton — —
7 Hamilton O. Smith — —
8 Mark D. Yandell —
9 Cheryl A. Evans — —
10 Robert A. Holt —
11 Jeannine D. Gocayne — —
12 Peter G. Amanatides — —
13 Richard M. Ballew —
14 Daniel H. Huson —
15 Jennifer Russo Wortman —
16 Qing Zhang —
17 Chinnappa D. Kodira — —
18 Xiangqun Zheng-Bradley —
19 Lin Chen —
20 Marian P. Skupski — —
21 G. Subramanian — —
22 Paul D. Thomas —
23 Jinghui Zhang —
24 George L. Gabor Miklos —
25 Catherine R. Nelson University of California, Berk… (US)
26 Samuel E. Broder — —
27 Andrew G. Clark Pennsylvania State University (US)
28 Joe Nadeau Case Western Reserve Universit… (US) —
29 Victor A. McKusick Johns Hopkins University (US) Johns Hopkins Medicine (US) +1 —
30 Norton D. Zinder Rockefeller University (US) —

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