Brodalumab: an evidence-based review of its potential in the…

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Brodalumab: an evidence-based review of its potential in the treatment of moderate-to-severe psoriasis

Review 2014 EN Diamond

Advances in knowledge regarding the pathogenesis of psoriasis have allowed the development of a new class of agents known as biologic drugs. Data confirm that T helper (Th)17 and interleukin (IL)-17 signaling has a crucial role in the pathogenesis of the disease. High levels of IL-17 and Th17-related cytokines have been reported in psoriasis, leading to the suggestion of agents targeting IL-17 as…

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3

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3 authors
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1 Susana Coimbra Corresponding Universidade do Porto (PT) Cooperativa de Ensino Superior… (PT) +1
2 Alice Santos‐Silva Corresponding Universidade do Porto (PT) Instituto de Biologia Molecula… (PT)
3 Américo Figueiredo Unidade Local de Saúde de Coim… (PT) University of Coimbra (PT)

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