Lung Fibrosis is Ameliorated by Pirfenidone Fed in Diet Afte…
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- DOI 10.3109/01902149809046058
- PMID https://pubmed.ncbi.nlm.nih.gov/9457473
- OpenAlex ID W2111985460
- Type Article
- Language EN
- Published 01 Jan 1998
- Volume 24 (1)
- Pages 119–133
- Source Experimental Lung Research
- Publisher Informa
- FWCI 4.30
- Countries 1
- Institutions 1
- Added 10 Oct 2025
- Updated 16 Oct 2026
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Lung Fibrosis is Ameliorated by Pirfenidone Fed in Diet After the Second Dose In A Three-Dose Bleomycin-Hamster Model
Article 1998 EN
Interstitial lung fibrosis (ILF) is a life-threatening disease which has no known drug for prevention and cure. In the present study, we evaluated the antifibrotic potential of pirfenidone (PD) (5-methyl-1-phenyl-2-(1H)-pyridone) in a three-dose bleomycin (BL)-hamster model of lung fibrosis. Hamsters were intratracheally (IT) instilled with three consecutive doses of bleomycin sulfate (2.5 U/kg/5m…
105
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39
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4
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4.30
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1 SDGsAuthors & Affiliations
4 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Swarnalatha N. Iyer | University of California, Davi… (US) | — |
| 2 | Solomon B. Margolin | — | — |
| 3 | Dallas M. Hyde | University of California, Davi… (US) | — |
| 4 | Shri N. Giri Corresponding | University of California, Davi… (US) | — |
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