Trafficking and signaling in mammalian autophagy
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- DOI 10.1002/iub.334
- PMID https://pubmed.ncbi.nlm.nih.gov/20552641
- OpenAlex ID W2107429225
- Type Review
- Language EN
- Published 26 Apr 2010
- Volume 62 (7)
- Pages 503–508
- Source IUBMB Life
- Publisher Wiley
- FWCI 0.73
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 27 Oct 2026
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Trafficking and signaling in mammalian autophagy
Review 2010 EN Bronze
Macroautophagy, here called autophagy, is literally a "self-eating" catabolic process, which is evolutionarily conserved. Autophagy is initiated by cellular stress pathways, resulting in the sequestration or engulfment of cytosolic proteins, membranes, and organelles in a double membrane structure that fuses with endosomes and lysosomes, thus delivering the sequestered material for degradation. Au…
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
11 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Sharon A. Tooze Corresponding | Cancer Research UK (GB) | |
| 2 | Harold B.J. Jefferies | Cancer Research UK (GB) | — |
| 3 | Eyal Kalie | Cancer Research UK (GB) | — |
| 4 | Andrea Longatti | Cancer Research UK (GB) | — |
| 5 | Fiona E McAlpine | Cancer Research UK (GB) | — |
| 6 | Nicole C. McKnight | Cancer Research UK (GB) | |
| 7 | Andrea Orsi | Cancer Research UK (GB) | |
| 8 | Hannah E.J. Polson | Cancer Research UK (GB) | — |
| 9 | Minoo Razi | Cancer Research UK (GB) | — |
| 10 | Deborah J. Robinson | Cancer Research UK (GB) | |
| 11 | Jemma L. Webber | Cancer Research UK (GB) |
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