Effect of phenobarbital on the pharmacokinetics of lidocaine…
Established
30
Citations23
Refs1997
Year
Search Works
Work Details
- PMID https://pubmed.ncbi.nlm.nih.gov/9172946
- OpenAlex ID W2103361287
- Type Article
- Language EN
- Published 01 Mar 1997
- Volume 25 (3)
- Pages 296–300
- Source PubMed
- Publisher National Institutes of Health
- FWCI 1.32
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 21 Sep 2026
External Links
MENU
0
Effect of phenobarbital on the pharmacokinetics of lidocaine, monoethylglycinexylidide and 3-hydroxylidocaine in the rat: correlation with P450 isoform levels.
Article 1997 EN
To elucidate the effect of cytochrome P450 levels in hepatic microsomes on the metabolism of lidocaine in vivo, we investigated the metabolism of lidocaine in untreated (UT group) and phenobarbital-treated rats (PB group) in vivo and compared the results with those obtained by immunoblotting of rat hepatic microsomes. There were no differences in pharmacokinetic parameters for lidocaine between th…
30
Citations
23
References
5
Authors
1.32
FWCI
Citations by Year
Last 4 yearsTopics
Keywords
UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
5 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | T Nakamoto | Osaka City University (JP) | — |
| 2 | Yutaka Oda | — | |
| 3 | Susumu Imaoka | — | — |
| 4 | Y Funae | — | — |
| 5 | Maiko Fujimori | — |
Related Works
10Data: OpenAlex