Liver X Receptor Activation Induces the Uptake of Cholestery…

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2008
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  • DOI 10.1161/atvbaha.108.175042
  • PMID https://pubmed.ncbi.nlm.nih.gov/18802017
  • OpenAlex ID W2095613717
  • Type Article
  • Language EN
  • Published 19 Sep 2008
  • Volume 28 (12)
  • Pages 2288–2295
  • Source Arteriosclerosis Thrombosis and Vascular…
  • Publisher Lippincott Williams & Wilkins
  • FWCI 4.85
  • Countries 1
  • Institutions 4
  • Added 10 Oct 2025
  • Updated 12 Oct 2026
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Liver X Receptor Activation Induces the Uptake of Cholesteryl Esters From High Density Lipoproteins in Primary Human Macrophages

Article 2008 EN Bronze

OBJECTIVE: Liver X receptors (LXRs) are oxysterol-activated nuclear receptors regulating reverse cholesterol transport, in part by modulating cholesterol efflux from macrophages to apoAI and HDL via the ABCA1 and ABCG1/ABCG4 pathways. Moreover, LXR activation increases intracellular cholesterol trafficking via the induction of NPC1 and NPC2 expression. However, implication of LXRs in the selective…

32

Citations

36

References

9

Authors

4.85

FWCI

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UN Sustainable Development Goals
1 SDGs
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9 authors
#AuthorInstitutionsORCID
1 S. Bultel Inserm (FR) Université de Lille (FR) +2 —
2 Lionel Helin Inserm (FR) Université de Lille (FR) +2 —
3 Véronique Barthelemy-Clavey Inserm (FR) Université de Lille (FR) +2 —
4 Giulia Chinetti Inserm (FR) Université de Lille (FR) +2
5 Elena Rigamonti Inserm (FR) Université de Lille (FR) +2 —
6 Morvane Colin Inserm (FR) Université de Lille (FR) +2
7 Jean‐Charles Fruchart Inserm (FR) Université de Lille (FR) +2 —
8 Bart Staels Inserm (FR) Université de Lille (FR) +2
9 Sophie Lestavel Inserm (FR) Université de Lille (FR) +2
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