Cooperative Recruitment of Dynamin and BIN/Amphiphysin/Rvs (…
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- DOI 10.1074/jbc.m112.444869
- PMID https://pubmed.ncbi.nlm.nih.gov/23297414
- OpenAlex ID W2088954489
- Type Article
- Language EN
- Published 08 Jan 2013
- Volume 288 (9)
- Pages 6651–6661
- Source Journal of Biological Chemistry
- Publisher Elsevier BV
- FWCI 9.10
- Countries 2
- Institutions 5
- Added 10 Oct 2025
- Updated 25 Oct 2026
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Cooperative Recruitment of Dynamin and BIN/Amphiphysin/Rvs (BAR) Domain-containing Proteins Leads to GTP-dependent Membrane Scission*
Article 2013 EN Hybrid
Dynamin mediates various membrane fission events, including the scission of clathrin-coated vesicles. Here, we provide direct evidence for cooperative membrane recruitment of dynamin with the BIN/amphiphysin/Rvs (BAR) proteins, endophilin and amphiphysin. Surprisingly, endophilin and amphiphysin recruitment to membranes was also dependent on binding to dynamin due to auto-inhibition of BAR-membran…
155
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47
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6
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9.10
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Authors & Affiliations
6 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Michael Meinecke Corresponding | MRC Laboratory of Molecular Bi… (GB) University of Göttingen (DE) +1 | |
| 2 | Emmanuel Boucrot | MRC Laboratory of Molecular Bi… (GB) Institute of Structural and Mo… (GB) +2 | |
| 3 | Gamze Ö. Çamdere | MRC Laboratory of Molecular Bi… (GB) Medical Research Council (GB) | — |
| 4 | Wai‐Ching Hon | MRC Laboratory of Molecular Bi… (GB) Medical Research Council (GB) | — |
| 5 | Rohit Mittal | MRC Laboratory of Molecular Bi… (GB) Medical Research Council (GB) | — |
| 6 | Harvey T. McMahon Corresponding | MRC Laboratory of Molecular Bi… (GB) Medical Research Council (GB) |
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