Relation of hypoxia inducible factor 1α and 2α in operable n…
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- DOI 10.1054/bjoc.2001.2018
- PMID https://pubmed.ncbi.nlm.nih.gov/11556841
- PMCID https://www.ncbi.nlm.nih.gov/pmc/articles/2375073
- OpenAlex ID W2085650758
- Type Article
- Language EN
- Published 01 Sep 2001
- Volume 85 (6)
- Pages 881–890
- Source British Journal of Cancer
- Publisher Springer Nature
- FWCI 10.73
- Countries 2
- Institutions 3
- Added 24 Jun 2016
- Updated 30 Oct 2026
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Relation of hypoxia inducible factor 1α and 2α in operable non-small cell lung cancer to angiogenic/molecular profile of tumours and survival
Article 2001 EN Hybrid
Hypoxia inducible factors HIF1alpha and HIF2alpha are important proteins involved in the regulation of the transcription of a variety of genes related to erythropoiesis, glycolysis and angiogenesis. Hypoxic stimulation results in rapid increase of the HIF1alpha and 2alpha protein levels, as a consequence of a redox-sensitive stabilization. The HIFalphas enter the nucleus, heterodimerize with the H…
477
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8
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10.73
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1 SDGsAuthors & Affiliations
8 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Alexandra N. Giatromanolaki | Democritus University of Thrac… (GR) | |
| 2 | Michael Ioannis Koukourakis | Democritus University of Thrac… (GR) | |
| 3 | Efthimios Sivridis | Democritus University of Thrac… (GR) | |
| 4 | Helen Turley | John Radcliffe Hospital (GB) University of Oxford (GB) | — |
| 5 | Kate Talks | John Radcliffe Hospital (GB) University of Oxford (GB) | — |
| 6 | Francesco Pezzella | John Radcliffe Hospital (GB) University of Oxford (GB) | |
| 7 | Kevin C. Gatter | John Radcliffe Hospital (GB) University of Oxford (GB) | — |
| 8 | Adrian Llewellyn Harris | John Radcliffe Hospital (GB) |
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