Inhibitory Effect of Poria cocos on 12-O-Tetradecanoylphorbo…

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Inhibitory Effect of Poria cocos on 12-O-Tetradecanoylphorbol-13-Acetate-Induced Ear Oedema and Tumour Promotion in Mouse Skin

Article 1996 EN

The methanol extract from the sclerotium of Poria cocos was found to inhibit 12-O-tetradecanoylphorbol-13-acetate (TPA)-induced tumour promotion in two-stage carcinogenesis in mouse skin. From the active fraction of the extract, eight lanostane-type triterpene acids and four 3,4-secolanostane-type triterpene acids were isolated. The isolated compounds showed inhibitory activity against TPA-induced…

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5 authors
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1 Tomohiro Kaminaga Nihon University (JP) —
2 Ken Yasukawa Corresponding Nihon University (JP)
3 Michio Takido Nihon University (JP) —
4 Takaaki Tai — —
5 Yoshiki Nunoura — —

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