Sustained Transduction of Ocular Cells with a Bovine Immunod…

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Sustained Transduction of Ocular Cells with a Bovine Immunodeficiency Viral Vector

Article 2002 EN

Human immunodeficiency viral (HIV) vectors mediate long-term transduction of many types of nondividing cells in vivo. Bovine immunodeficiency virus (BIV) is a lentivirus that shares many characteristics with HIV, but does not cause human disease. In this study, we investigated the potential of BIV vectors for ocular gene therapy. An enhanced green fluorescent protein (eGFP)-encoding reporter gene…

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9 authors
#AuthorInstitutionsORCID
1 Kyoichi Takahashi Johns Hopkins University (US) Johns Hopkins Medicine (US) —
2 Tianci Luo — —
3 Yoshitsugu Saishin Johns Hopkins University (US) Johns Hopkins Medicine (US)
4 Yumiko Saishin Johns Hopkins University (US) Johns Hopkins Medicine (US) —
5 Jennifer Sung Johns Hopkins University (US) Johns Hopkins Medicine (US) —
6 Sean F. Hackett Johns Hopkins University (US) Johns Hopkins Medicine (US) —
7 Romulus K. Brazzell — —
8 Michael Kaleko —
9 Peter A. Campochiaro Johns Hopkins University (US) Johns Hopkins Medicine (US)

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