Evidence that Hyperglycemia Increases Muscarinic Binding in …
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- DOI 10.1210/endo-121-5-1705
- PMID https://pubmed.ncbi.nlm.nih.gov/3311716
- OpenAlex ID W2060255031
- Type Article
- Language EN
- Published 01 Nov 1987
- Volume 121 (5)
- Pages 1705–1710
- Source Endocrinology
- Publisher Oxford University Press
- FWCI 2.66
- Countries 1
- Institutions 1
- Added 10 Oct 2025
- Updated 21 Aug 2026
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Evidence that Hyperglycemia Increases Muscarinic Binding in Pancreatic Islets of the Rat*
Article 1987 EN
We studied the effects of fasting and of diabetes on binding of [3H]methylscopolamine to pancreatic islets of the rat. In nondiabetic rats, fasting for 36 h decreased binding of the muscarinic antagonist by 33% (P less than 0.05). Fasting also abolished the insulin response to 10 microM acetylcholine. Diabetes was induced by injecting streptozotocin (STZ) neonatally in rats. At the time of the exp…
28
Citations
23
References
2
Authors
2.66
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
2 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Claes‐Göran Östenson | Karolinska University Hospital (SE) | |
| 2 | Valdemar Grill | Karolinska University Hospital (SE) |
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