The Ontogeny of Scarless Healing II: EGF and PDGF-B Gene Expression in Fetal Rat Skin and Fibroblasts as a Function of Gestational Age

Twenty years ago, surgeons noted the ability of early-gestation fetal skin to heal in a scarless manner. Since that time, numerous investigators have attempted to elucidate the mechanisms behind this phenomenon. As a result of this effort, it is now well established that many animals undergo a transition late in development from scarless cutaneous healing to a scar-forming, adultlike phenotype. Th…