A one-pot isoquinoline synthesis by cyclodehydrogenation of …
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- DOI 10.1248/cpb.35.4964
- OpenAlex ID W2038484385
- Type Article
- Language EN
- Published 01 Jan 1987
- Volume 35 (12)
- Pages 4964–4966
- Source Chemical and Pharmaceutical Bulletin
- Publisher Pharmaceutical Society of Japan
- FWCI 0.25
- Countries 1
- Institutions 1
- Added 24 Jun 2016
- Updated 04 Aug 2026
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A one-pot isoquinoline synthesis by cyclodehydrogenation of N-benzyl-.ALPHA.-alkylaminoacetals with chlorosulfonic acid. Formation of 3-alkylisoquinolines.
Article 1987 EN Bronze
A direct preparation of fully aromatized 3-alkylisoquinolines (3e-p), was achieved by cyclodehydrogenation with chlorosulfonic acid of N-benzyl-α-alkylaminoacetals (2e-p) which were prepared by addition of Grignard reagent to N-benzyliminoacetals (1a-d).
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2 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | KAZUKO KIDO | Daiichi University of Pharmacy (JP) | — |
| 2 | YASUO WATAINABE | Daiichi University of Pharmacy (JP) | — |
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