Establishment of the micronucleus assay in the human hepatom…

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  • DOI 10.1055/s-0028-1084971
  • OpenAlex ID W2032098058
  • Type Article
  • Language EN
  • Published 01 Jul 2008
  • Volume 74 (09)
  • Source Planta Medica
  • Publisher Thieme Medical Publishers (Germany)
  • Countries 1
  • Institutions 1
  • Added 24 Jun 2016
  • Updated 14 Oct 2026
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Establishment of the micronucleus assay in the human hepatoma cell line HepG2 to identify genotoxic natural products

Article 2008 EN

Alternative therapies become more and more popular. Indeed a lot of herbal preparations are hardly toxicologically analysed. According to the OECD guideline [1] the cytokinesis-block micronucleus assay (CBMN assay) has been established in the human hepatoma cell line HepG2 to identify genotoxic natural products. The CBMN assay is used to detect chemicals, which generate structural (clastogenic) or…

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UN Sustainable Development Goals
1 SDGs
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2 authors
#AuthorInstitutionsORCID
1 Dana Nitzsche Freie Universität Berlin (DE) —
2 Matthias F. Melzig Freie Universität Berlin (DE) —

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