Inhibition of Human Gastric Acid Secretion by Peptide YY and…

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Inhibition of Human Gastric Acid Secretion by Peptide YY and Secretin

Article 2009 EN

In 6 healthy volunteers we investigated the effect of secretin and peptide YY (PYY) on gastric acid secretion stimulated by pentagastrin (100 ng/kg/h). Secretin (0.05 CU/kg/h) and PYY (10.0 pmol/kg/h) were given intravenously either alone or in combination. Given alone secretin and PYY inhibited gastric acid output by 25 and 21%, respectively. The combined infusion of secretin and PYY inhibited ac…

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1 Ole Olsen University of Copenhagen (DK) Glostrup Hospital (DK)
2 John Christiansen — —

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