In Vivo Reverse Cholesterol Transport From Macrophages Lacki…
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- DOI 10.1161/atvbaha.107.146068
- PMID https://pubmed.ncbi.nlm.nih.gov/17541020
- OpenAlex ID W2015209966
- Type Article
- Language EN
- Published 01 Jun 2007
- Volume 27 (8)
- Pages 1837–1842
- Source Arteriosclerosis Thrombosis and Vascular…
- Publisher Lippincott Williams & Wilkins
- FWCI 5.65
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 14 Oct 2026
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In Vivo Reverse Cholesterol Transport From Macrophages Lacking ABCA1 Expression Is Impaired
Article 2007 EN Bronze
BACKGROUND: ATP-binding cassette transporter A1 (ABCA1) is a key mediator of cholesterol efflux to apoA-I in cholesterol loaded macrophages, a first step of reverse cholesterol transport (RCT) in vivo. Macrophage specific abca1 inactivation or overexpression, respectively, accelerated or suppressed the development of atherosclerosis in mouse models. However, it is yet to be established that the AB…
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3
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1 SDGsAuthors & Affiliations
3 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Mingdong Wang | University of Ottawa (CA) Ottawa Heart Institute (CA) | |
| 2 | Vivian Franklin | University of Ottawa (CA) Ottawa Heart Institute (CA) | — |
| 3 | Yves L. Marcel | University of Ottawa (CA) Ottawa Heart Institute (CA) | — |
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