Longitudinal Study on the Establishment of Insulin Resistanc…

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99
Citations
43
Refs
1978
Year
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Work Details
  • DOI 10.1210/endo-102-1-74
  • PMID https://pubmed.ncbi.nlm.nih.gov/369821
  • OpenAlex ID W2010484394
  • Type Article
  • Language EN
  • Published 01 Jan 1978
  • Volume 102 (1)
  • Pages 74–85
  • Source Endocrinology
  • Publisher Oxford University Press
  • FWCI 8.13
  • Countries 1
  • Institutions 1
  • Added 10 Oct 2025
  • Updated 12 Oct 2026
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Longitudinal Study on the Establishment of Insulin Resistance in Hypothalamic Obese Mice*

Article 1978 EN

A longitudinal in vivo and in vitro analysis of the genesis of insulin resistance has been carried out in mice made obese by chemical made obese by chemical lesion (goldthioglucose, GTG) of the hypothalamus. Six weeks after GTG administration, glycemia and glucose disposal were normal but associated with increased insulin concentration, suggesting incipient insulin resistance. The in vitro counter…

99

Citations

43

References

3

Authors

8.13

FWCI

Topics
Keywords
UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
3 authors
#AuthorInstitutionsORCID
1 Yannick LE MARCHAND‐BRUSTEL Inserm (FR) —
2 Pierre Freychet Inserm (FR) —
3 Bernard Jeanrenaud Inserm (FR) —

Data: OpenAlex