Transduction of ferret airway epithelia using a pre-treatmen…

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Transduction of ferret airway epithelia using a pre-treatment and lentiviral gene vector

Article 2014 EN Gold

BACKGROUND: The safety and efficiency of gene therapies for cystic fibrosis (CF) need to be assessed in pre-clinical models. Using the normal ferret, this study sought to determine whether ferret airway epithelia could be transduced with a lysophosphatidylcholine (LPC) pre-treatment followed by a VSV-G pseudotyped HIV-1 based lentiviral (LV) vector, in preparation for future studies in CF ferrets.…

15

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23

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7

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1.31

FWCI

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7 authors
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1 Patricia Cmielewski Corresponding Women's and Children's Hospita… (AU) Women's and Children's Health … (AU)
2 Nigel Farrow Women's and Children's Hospita… (AU) Women's and Children's Health … (AU) +1
3 Martin Donnelley Women's and Children's Hospita… (AU) Women's and Children's Health … (AU) +1
4 Chantelle McIntyre Women's and Children's Hospita… (AU) Women's and Children's Health … (AU) +1 —
5 Jahan C. Penny‐Dimri The University of Adelaide (AU)
6 Tim R. Kuchel South Australian Health and Me… (AU)
7 David Parsons Women's and Children's Hospita… (AU) The University of Adelaide (AU)

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