Development of safer molecules through chirality
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- DOI 10.4103/0019-5359.27676
- PMID https://pubmed.ncbi.nlm.nih.gov/17006031
- OpenAlex ID W1993949372
- Type Article
- Language EN
- Published 01 Jan 2006
- Volume 60 (10)
- Pages 427
- Source Indian Journal of Medical Sciences
- Publisher Medknow
- FWCI 1.33
- Countries 1
- Institutions 2
- Added 24 Jun 2016
- Updated 12 Oct 2026
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Development of safer molecules through chirality
Article 2006 EN Green
Many of the drugs currently used in medical practice are mixtures of enantiomers (racemates). Many a times, the two enantiomers differ in their pharmacokinetic and pharmacodynamic properties. Replacing existing racemates with single isomers has resulted in improved safety and/or efficacy profile of various racemates. In this review, pharmacokinetic and pharmacodynamic implications of chirality are…
44
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55
References
2
Authors
1.33
FWCI
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UN Sustainable Development Goals
1 SDGsAuthors & Affiliations
2 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | MA Kothekar | Emcure Pharmaceuticals (India) (IN) | — |
| 2 | PA Patil | Jawaharlal Nehru Medical Colle… (IN) | — |
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