DNA Methylation Landscapes of Human Fetal Development
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- DOI 10.1371/journal.pgen.1005583
- PMID https://pubmed.ncbi.nlm.nih.gov/26492326
- OpenAlex ID W1944020248
- Type Article
- Language EN
- Published 22 Oct 2015
- Volume 11 (10)
- Pages e1005583
- Source PLoS Genetics
- Publisher Public Library of Science
- FWCI 4.03
- Countries 2
- Institutions 3
- Added 24 Jun 2016
- Updated 27 Oct 2026
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DNA Methylation Landscapes of Human Fetal Development
Article 2015 EN Gold
Remodelling the methylome is a hallmark of mammalian development and cell differentiation. However, current knowledge of DNA methylation dynamics in human tissue specification and organ development largely stems from the extrapolation of studies in vitro and animal models. Here, we report on the DNA methylation landscape using the 450k array of four human tissues (amnion, muscle, adrenal and pancr…
97
Citations
71
References
10
Authors
4.03
FWCI
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Authors & Affiliations
10 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Roderick C. Slieker | Leiden University Medical Cent… (NL) | |
| 2 | Matthias S. Roost | Leiden University Medical Cent… (NL) | |
| 3 | Liesbeth van Iperen | Leiden University Medical Cent… (NL) | — |
| 4 | H. Eka D. Suchiman | Leiden University Medical Cent… (NL) | |
| 5 | Elmar W. Tobi | Leiden University Medical Cent… (NL) | |
| 6 | Françoise Carlotti | Leiden University Medical Cent… (NL) | |
| 7 | Eelco J.P. de Koning | Leiden University Medical Cent… (NL) Hubrecht Institute for Develop… (NL) | |
| 8 | P. Eline Slagboom | Leiden University Medical Cent… (NL) | |
| 9 | Bastiaan T. Heijmans Corresponding | Leiden University Medical Cent… (NL) | |
| 10 | Susana M. Chuva de Sousa Lopes Corresponding | Leiden University Medical Cent… (NL) Ghent University Hospital (BE) |
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