CFTR Inactivation by Lentiviral Vector-mediated RNA Interfer…
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- DOI 10.2174/1566523215666150812115939
- PMID https://pubmed.ncbi.nlm.nih.gov/26264708
- OpenAlex ID W1844228885
- Type Article
- Language EN
- Published 25 Aug 2015
- Volume 15 (5)
- Pages 447–459
- Source Current Gene Therapy
- Publisher Bentham Science Publishers
- FWCI 4.48
- Countries 2
- Institutions 6
- Added 24 Jun 2016
- Updated 27 Oct 2026
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CFTR Inactivation by Lentiviral Vector-mediated RNA Interference and CRISPR-Cas9 Genome Editing in Human Airway Epithelial Cells
Article 2015 EN Green
BACKGROUND: Polarized airway epithelial cell cultures modelling Cystic Fibrosis Transmembrane conductance Regulator (CFTR) defect are crucial for CF and biomedical research. RNA interference has proven its value to generate knockdown models for various pathologies. More recently, genome editing using CRISPR-Cas9 artificial endonuclease was a valuable addition to the toolbox of gene inactivation. M…
46
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57
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6
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4.48
FWCI
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1 SDGsAuthors & Affiliations
6 authors| # | Author | Institutions | ORCID |
|---|---|---|---|
| 1 | Jessica Bellec | Inserm (FR) Centre Hospitalier Universitai… (FR) +2 | — |
| 2 | Marc Bacchetta | University of Geneva (CH) University Hospital of Geneva (CH) | — |
| 3 | Davide Losa | University of Geneva (CH) University Hospital of Geneva (CH) | |
| 4 | Ignacio Anegón | Inserm (FR) Centre Hospitalier Universitai… (FR) +2 | |
| 5 | Marc Chanson | — | |
| 6 | Tuan M. Nguyen | Inserm (FR) Centre Hospitalier Universitai… (FR) +2 |
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