Autophagy Is Induced in CD4+ T Cells and Important for the G…

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  • DOI 10.4049/jimmunol.177.8.5163
  • PMID https://pubmed.ncbi.nlm.nih.gov/17015701
  • OpenAlex ID W1559838741
  • Type Article
  • Language EN
  • Published 01 Oct 2006
  • Volume 177 (8)
  • Pages 5163–5168
  • Source The Journal of Immunology
  • Publisher American Association of Immunologis…
  • FWCI 11.42
  • Countries 1
  • Institutions 3
  • Added 24 Jun 2016
  • Updated 25 Oct 2026
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Autophagy Is Induced in CD4+ T Cells and Important for the Growth Factor-Withdrawal Cell Death

Article 2006 EN

Autophagy is a tightly regulated catabolic mechanism that degrades proteins and organelles. Autophagy mediates programmed cell death under certain conditions. To determine the role of autophagy in T cells, we examined, in mouse CD4+ T cells, conditions under which autophagy is induced and alterations of the cell fate when autophagy is blocked. We have found that resting naive CD4+ T cells do not c…

278

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39

References

8

Authors

11.42

FWCI

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UN Sustainable Development Goals
1 SDGs
Authors & Affiliations
8 authors
#AuthorInstitutionsORCID
1 Changyou Li University of Pittsburgh (US)
2 Elizabeth Capan University of Pittsburgh (US) —
3 Yani Zhao University of Pittsburgh (US)
4 Jianping Zhao University of Pittsburgh (US)
5 Donna Beer Stolz University of Pittsburgh (US)
6 Simon C. Watkins University of Pittsburgh (US)
7 Shengkan Jin University of Medicine and Den… (US) —
8 Binfeng Lu University of Pittsburgh (US) UPMC Hillman Cancer Center (US)

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